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Scientific and Educational Publications









Recent Presentations from the Brandt Lab

Shibberu, Y., Brandt, M.E., and Cooper D.R. Intrinsic Contact Geometry of Protein Dynamics. 2010 International Conference on Bioinformatics and Computational Biology (BIOCOMP10), Las Vegas, NV, July, 2010.

Shibberu, Y., and Brandt, M.E., Contact Geometry of Estrogen Receptor Dynamics. 20th Annual International Conference on Intelligent Systems for Molecular Biology, Long Beach, CA, July, 2012.

Brandt, M.E., and Shibberu, Y. Problem-Based Interdisciplinary Learning in an Undergraduate Computational Biochemistry Course. 21st Annual International Conference on Intelligent Systems for Molecular Biology, Berlin, Germany, July, 2013.

Maled, B., Bauhan, D., and Brandt, M.E. Sub-cloning of Estrogen Receptor beta. 25th Annual Butler Undergraduate Research Conference, Indianapolis, IN, April, 2013.

Watson, G., Shibberu, Y., and Brandt, M.E. Statistical Analysis and Empirical Modeling of Physical Properties of Alcohols and Related Solvents. 10th Annual IRC Undergraduate Research Symposium, Terre Haute, IN, October, 2013.

Hiance, J., Shibberu, Y., and Brandt, M.E. Simulating the Dimerization Process of the Estrogen Receptor Protein. 10th Annual IRC Undergraduate Research Symposium, Terre Haute, IN, October, 2013.


Selected Research Publications

Brandt, R.B., Brandt, M.E., April, M.E., and Thomson, C. Potential Transition-State Inhibitors of Glyoxalase I. Internat. J. of Quantum Chem., Quantum Biol. Symposium 9: 335-343, 1982.

Brandt, R.B., Brandt, M.E., April, M.E., and Thomson, C. Inhibitors of Glyoxalase I in vitro. Biochemical Med. 29: 385-391, 1983. [Pubmed Abstract]

Zimniski, S.J., Brandt, M.E., Melner, M.H., Covey, D.F., and Puett, D. Inhibition of Leydig Tumor Cell Steroidogenesis by 10-Propargylestr-4-ene-3,17-dione, an Irreversible Aromatase Inhibitor. Cancer Res. 45: 4883-4889, 1985. [Pubmed Abstract]

Zimniski, S.J., Brandt, M.E., Covey, D.F., and Puett, D. Inhibition of Aromatase Activity and of Endocrine-Responsive Tumor Growth by 10-Propargylestr-4-ene-3,17-dione and Its 17-Propionate Derivative. Steroids 50: 135-146, 1987. [Pubmed Abstract]

Brandt, M.E., Puett, D., Covey, D.F., and Zimniski, S.J. Characterization of Pregnant Mare's Serum Gonadotropin-Stimulated Rat Ovarian Aromatase and Its Inhibition by 10-Propargylestr-4-ene-3,17-dione. J. Steroid Biochem. 31: 317-324, 1988. [Pubmed Abstract]

Brandt, M.E., Puett, D., and Zimniski, S.J. Divergence between Ovarian Aromatase Activity, Estrogen, and Androgen Levels in the Cycling Rat. Endocrinology 126: 72-79, 1990. [Pubmed Abstract]

Brandt, M.E., Covey, D.F., and Zimniski, S.J. The Effects of in vivo Administration of 10-Propargylestr-4-ene-3,17-dione on Rat Ovarian Aromatase and Estrogen Levels. J. Enzyme Inhib. 4: 143-152, 1990. [Pubmed Abstract]

Brandt, M.E., Gabrik, A.H., and Vickery, L. E. A Vector for Directional Cloning and Expression of Polymerase Chain Reaction Products in Escherichia coli. Gene 97: 113-117, 1991. [Pubmed Abstract]

El-Maasarany, S., Brandt, M.E., Majercik, M.H., Zimniski, S.J., and Puett, D. Immunocytochemical Localization and Enzymatic Distribution of Rat Ovarian Aromatase. Biol. Reprod.44: 550-560, 1991. [Pubmed Abstract]

Zimniski, S.J., Brandt, M.E., Melner, M.H., Covey, D.F., and Puett, D. Effects of 4-Hydroxyandrostenedione on Murine Leydig Tumor Cell Steroidogenesis. Cancer Res. 51: 3663-3668, 1991. [Pubmed Abstract]

Schlaepfer D.D., Fisher, D.A., Brandt, M.E., Bode, H.R., Jones, J.M., and Haigler, H.T. Identification of a Novel Annexin in Hydra Vulgaris: Characterization, cDNA Cloning, and Protein Kinase C Phosphorylation of Annexin XII. J. Biol. Chem.267:9529-9539, 1992. [Pubmed Abstract]

Brandt, M.E. and Vickery, L.E. Expression and Characterization of Human Mitochondrial Ferredoxin Reductase in Escherichia coli. Arch. Biochem. Biophys. 294: 735-740, 1992. [Pubmed Abstract]

Zimniski, S.J., Brandt, M.E., Covey, D.F., and Puett, D. Inhibition of Growth and Appearance of Estrogen-Dependent Rat Mammary Tumors by 10-Propargylestr-4-ene-3,17-dione, an Aromatase Inhibitor. Breast Can. Res. Treat. 26: 15-21, 1993. [Pubmed Abstract]

Brandt, M.E. and Vickery, L.E. Charge Pair Interactions Stabilizing Ferredoxin-Ferredoxin Reductase Complexes: Identification by Complementary Site-Specific Mutations. J. Biol. Chem. 268: 17126-17130, 1993. [Pubmed Abstract]

Please note:  The copyrights to the publications listed below are held by their publishers.  The pdf files provided may be used only for single copies for personal use, as though they were reprints provided by mail.  They may not be reposted on other web sites or used for any other purpose without the express permission of the appropriate publishers. 

Brandt, M.E. and Vickery, L.E. Cooperativity and Dimerization of Recombinant Human Estrogen Receptor Hormone Binding Domain. J. Biol. Chem. 272: 4843-4849, 1997. [File size: 310 kb][Pubmed Abstract]

Gomez-Casati, D.F., Igarashi R.Y., Berger, C.N., Brandt, M.E., Alberto A. Iglesias, A.A., and Meyer, C.R. Identification of Functionally Important Amino Terminal Arginines of Agrobacterium tumefaciens ADP-Glucose Pyrophosphorylase by Alanine-Scanning Mutagenesis. Biochemistry 40: 10169-10178, 2001. [File size: 116 kb] [PubMed Abstract]


Book Chapters and Reviews

Puett, D., Brandt, M.E., Covey, D.F., and Zimniski, S.J. Characterization of a Potent Inhibitor of Aromatase: Inhibition of the Rat Ovarian Enzyme and Regression of Estrogen-Dependent Mammary Tumors by 10-Propargylestr-4-ene-3,17-dione. In: Endocrinology and Malignancy: Basic and Clinical Issues, E.E. Baulieu, S. Iacobelli, and W.L. McGuire, eds. (The Parthenon Publishing Group, Carnforth, England, 1986, pp. 278-289)

Brandt, M.E., Puett, D., Garola, R., Fendl, K., Covey, D.F., and Zimniski, S. J. Aromatase and Aromatase Inhibitors: From Enzymology to Selective Chemotherapy. In: Hormones, Cell Biology, and Cancer: Potentials and Perspectives, W.D. Hankins and D. Puett, eds. (Alan R. Liss Publishing. Co., New York, 1988, pp. 65-84). [Pubmed]

Holder, A., Brandt, M.E., and Shibberu, Y. Fundamentals of Protein Structure Alignment. Mathematical Sciences Technical Reports (MSTR). Paper 1.

Laboratory Manuals

Please note:  The copyrights to the publications listed below are held by Mark Brandt, Ph.D.  Instructors may use these files in teaching their classes, on the condition that you obtain permission and give appropriate credit to the author. Students are welcome to use these files to assist in your mastery of biochemistry.

Brandt, M.E. Chemistry 422 Biochemistry Laboratory Manual. (Custom Publishing, California State University, Fullerton, California, 2001, 2002). [File size: 832 kb]


Brandt, M.E. Chemistry 472B Biotechnology Laboratory Manual. (Custom Publishing, California State University, Fullerton, California, 2002). [File size: 794 kb]




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